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Marine Collagen Peptides
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Collagen supplementation is very effective in improving skin quality and texture, even in specific cases such as cellulite.
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Schunck M, Zague V, Oesser S, Proksch E. Dietary Supplementation with Specific Collagen Peptides Has a Body Mass Index-DependentBeneficial Effect on Cellulite Morphology. J Med Food. 2015 Dec;18(12):1340-8. doi: 10.1089/jmf.2015.0022. Epub 2015 Nov 12. PMID:26561784; PMCID: PMC4685482.
Choi, F.D.; Sung, C.T.; Juhasz, M.L.; Mesinkovsk, N.A. Oral Collagen Supplementation: A Systematic Review of DermatologicalApplications. J. Drugs. Dermatol. 2019, 18, 9–16. https://pubmed.ncbi.nlm.nih.gov/30681787/
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Hyaluronic acid
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The effects of oral hyaluronic acid have been extensively studied for its anti-aging properties and dermal remodeling action. It may improve the appearance of cellulite by helping to reorganize the dermal compartment and hydrating the skin's surface.
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Papakonstantinou E, Roth M, Karakiulakis G. Hyaluronic acid: A key molecule in skin aging. Dermatoendocrinol. 2012;4(3):253-258.
doi:10.4161/derm.21923
Meyer LJ, Stern R. Age-dependent changes of hyaluronan in human skin. J Invest Dermatol 1994; 102:385- 9; PMID:8120424;
http://dx.doi.org/10.1111/1523- 1747.ep12371800
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Acerola extract - Vitamin C
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Numerous scientific studies highlight the beneficial role of vitamin C on the skin. Oral vitamin C supplementation helps fight skin oxidation and can also stimulate collagen production in the dermis, improve skin firmness and elasticity, and thus visibly reduce the appearance of cellulite.
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Pullar J.M., Carr A.C., Vissers M.C.M. The roles of vitamin C in skin health. Nutrients. 2017; 9:866–892.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5579659/
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Vitamin E
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Fat-soluble vitamin E can help fight cellulite thanks to its antioxidant and anti-inflammatory properties. It can also improve skin quality by supporting microcirculation and reducing skin inflammation.
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Maalouf S, El-Sabban M, Darwiche N, Gali-Muhtasib H. Protective effect of vitamin E on ultraviolet B light-induced damage inkeratinocytes. Mol Carcinog. 2002;34:121–30. https://pubmed.ncbi.nlm.nih.gov/12112306/
Musalmah M, Fairuz AH, Gapor MT, Ngah WZ. Effect of vitamin E on plasma malondialdehyde, antioxidant enzyme levels and the ratesof wound closures during wound healing in normal and diabetic rats. Asia Pac J Clin Nutr. 2002;11 Suppl 7:S448-451. (PubMed)
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Green tea extract
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Among the benefits of tea tree and its extracts, it is worth highlighting their value in anti-aging treatments and their slimming properties. Their constituents are also effective in improving skin microcirculation and offer general antioxidant benefits.
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Heinrich, U.; Moore, C.E.; De Spirt, S.; Tronnier, H.; Stahl,W. Green tea polyphenols provide photoprotection, increasemicrocirculation, and modulate skin properties of women. J. Nutr. 2011, 141, 1202–1208.
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Lipase
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As a digestive enzyme, it supports the breakdown of fats, which can contribute to better metabolic balance.
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A. Jawed, G. Singh, S. Kohli, A. Sumera, S. Haque, R. Prasad, D. Paul, Therapeutic role of lipases and lipase inhibitors derived from naturalresources for remedies against metabolic disorders and lifestyle diseases, South African Journal of Botany, Volume 120, 2019, Pages 25-32,ISSN 0254-6299, https://doi.org/10.1016/j.sajb.2018.04.004.
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Gotu-kola extract
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Centella asiatica has been used for centuries in traditional medicine to improve the venous system. It strengthens connective tissue and can therefore have a positive effect on vascularization, which can help reduce cellulite.
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L. Incandela, M.R. Cesarone, M. Cacchio, M.T. DeSanctis, C. Santavenere, and M.G. D’Auro,“Total triterpenic fraction of Centellaasiatica in chronic venous insufficiency and in high perfusion microangiopathy,”Angiology, vol. 52, pp.9–13,2001.
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Guarana extract
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Due to its caffeine content, it can reduce adipogenesis, stimulate energy expenditure and support weight management.
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Torres EAFS, Pinaffi-Langley ACDC, Figueira MS, Cordeiro KS, Negrão LD, Soares MJ, da Silva CP, Alfino MCZ, Sampaio GR, de CamargoAC. Effects of the consumption of guarana on human health: A narrative review. Compr Rev Food Sci Food Saf. 2022 Jan;21(1):272-295. doi:10.1111/1541-4337.12862. Epub 2021 Nov 9. PMID: 34755935.
Torres, E. A. F. S., Pinaffi-Langley, A. C. D. C., Figueira, M. S., Cordeiro, K. S., Negrão, L. D., Soares, M. J., da Silva, C. P., Alfino, M. C. Z., Sampaio, G. R., & de Camargo, A. C. (2022). Effects of the consumption of guarana on human health: A narrative review. Comprehensive reviews in food science and food safety, 21(1), 272–295. https://doi.org/10.1111/1541-4337.12862
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Turmeric extract
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Overall, in vitro and clinical data suggest that curcumin has multiple actions on low-grade inflammation observed in overweight and obese conditions.
From a clinical perspective, curcumin extracts exhibit fat-reducing activities and positive effects on body composition.
Curcumin helps modulate chronic inflammation associated with obesity. It may help improve body composition and reduce the visible signs of cellulite.
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Akbari M, Lankarani KB, Tabrizi R, Ghayour-Mobarhan M, Peymani P, Ferns G, Ghaderi A, Asemi Z. The Effects of Curcumin on WeightLoss Among Patients With Metabolic Syndrome and Related Disorders: A Systematic Review and Meta-Analysis of Randomized ControlledTrials. Front Pharmacol. 2019 Jun 12;10:649. doi: 10.3389/fphar.2019.00649. PMID: 31249528; PMCID: PMC6582779.
Daily, J. W., Yang, M., & Park, S. (2016). Efficacy of Turmeric Extracts and Curcumin for Alleviating the Symptoms of Joint Arthritis: A Systematic Review and Meta-Analysis of Randomized Clinical Trials. Journal of medicinal food, 19(8), 717–729. https://doi.org/10.1089/jmf.2016.3705
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SOD (melon extract)
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By neutralizing free radicals, SOD may act at various levels to prevent and reduce cellulite. Supported by in vitro, mechanistic, and clinical studies, SOD Dimpless® demonstrates good efficacy against cellulite. It acts through a dual mechanism, both on adipocytes and on fibrosis, which suggests that this ingredient may also have an effect on the surrounding extracellular matrix.
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Egoumenides L, Gauthier A, Barial S, Saby M, Orechenkoff C, Simoneau G, Carillon J. A Specific Melon Concentrate ExhibitsPhotoprotective Effects from Antioxidant Activity in Healthy Adults. Nutrients. 2018 Mar 31;10(4):437. doi: 10.3390/nu10040437. PMID:29614719; PMCID: PMC5946222. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946222/
Lemaire B, Le Quéré S, Lacan D. Clinical trial of a natural and bioactive melon SuperOxide Dismutase on cellulite. Phytothérapie. 2015;13(6):372–376. doi:10.1007/s10298-015-0963-5
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Biomimetic peptide
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Mimics the natural action of skin proteins to stimulate regeneration and reduce the appearance of wrinkles.
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Ferulic acid
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Powerful antioxidant that neutralizes free radicals and enhances the effectiveness of vitamins C and E.
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